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Indications

• Hydralazine is used alone or in combination with other medications to treat high blood pressure.
• The primary goal is to lower high blood pressure, reducing the risk of strokes, heart attacks, and kidney problems.
• Hydralazine is classified as a vasodilator, functioning by relaxing blood vessels.
• Its mechanism of action involves the dilation of blood vessels, facilitating smoother blood flow throughout the body.

Dosage and administration

• Take hydralazine by mouth, with or without food, as directed by your doctor, usually 2 to 4 times daily.
• The dosage is determined based on your medical condition and how you respond to treatment.
• Your doctor may initiate treatment with a low dose, gradually increasing it. Adhere to your doctor’s instructions.
• Use the medication regularly to maximize its benefits, taking it at the same times each day.
• Continue taking the medication even if you feel well, as high blood pressure may not exhibit noticeable symptoms.
• It might take several weeks before experiencing the full benefits of the drug.
• Do not stop taking hydralazine without consulting your doctor, as abrupt discontinuation may worsen certain conditions. If needed, your dose will be gradually reduced.
• Inform your doctor if your condition deteriorates, such as an increase in routine blood pressure readings.

Side effects

• Possible side effects of hydralazine may include headache, fast heartbeat, loss of appetite, nausea, vomiting, diarrhea, or dizziness as your body adjusts to the medication.
• If these effects persist or worsen, inform your doctor or pharmacist promptly.
• To minimize the risk of dizziness, rise slowly when getting up from a sitting or lying position.
• This medication is prescribed because its benefits outweigh the potential side effects. Many individuals using hydralazine do not experience serious side effects.
• Rarely, hydralazine may cause nerve problems. Notify your doctor promptly if you experience numbness or tingling. Your doctor may recommend a vitamin B6 supplement (pyridoxine).
• Report immediately to your doctor if you have severe tiredness, swollen joints, rash on the nose and cheeks, swollen glands, signs of kidney problems, signs of infection, or easy bruising/bleeding.
• Seek medical assistance urgently if you experience chest/jaw/left arm pain.
• While a severe allergic reaction is rare, get medical help immediately if you observe symptoms such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.
• This list does not cover all possible side effects, so contact your doctor or pharmacist if you notice any other effects not listed.

Precautions

• Before taking hydralazine, inform your doctor or pharmacist about any allergies you may have, as inactive ingredients in the product can cause allergic reactions.
• Provide your medical history, especially if you have heart problems, blood vessel issues, a history of stroke, or kidney problems.
• Hydralazine may cause dizziness. Avoid activities that require alertness, such as driving or using machinery, until you can do them safely. Limit alcohol intake and discuss marijuana use with your doctor.
• Before undergoing surgery, inform your doctor or dentist about all the products you use, including prescription drugs, nonprescription drugs, and herbal products.
• Older adults may be more sensitive to the side effects of hydralazine, particularly dizziness, which can increase the risk of falls.
• During pregnancy, use this medication only if clearly needed. Discuss the risks and benefits with your doctor.
• Hydralazine passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before breastfeeding.