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Indications

• Exemestane is utilized for treating specific types of breast cancer, particularly hormone-receptor-positive breast cancer, in postmenopausal women.
• Its purpose extends to preventing the cancer from recurring.
• Certain breast cancers are stimulated by the hormone estrogen; Exemestane reduces estrogen production, slowing or reversing the growth of these cancers.
• Typically, Exemestane is not prescribed for women of childbearing age.

Dosage and administration

• Before starting Exemestane, read the Patient Information Leaflet from your pharmacist. Seek clarification from your doctor or pharmacist if you have any questions.
• Take this medication orally with food, as directed by your doctor, usually once daily.
• Dosage depends on your medical condition, response to treatment, and other medications you may be using. Inform your doctor and pharmacist about all products you use, including prescriptions, non-prescriptions, and herbal items.
• Use the medication regularly to maximize its benefits. Take it at the same time each day to help remember.
• As the drug can be absorbed through the skin and lungs, pregnant women or those planning to become pregnant should avoid handling the medication or inhaling tablet dust (refer to Precautions section).
• Notify your doctor promptly if your condition worsens, such as the development of new breast lumps.

Side effects

• Possible side effects of Exemestane may include hot flashes, hair loss, bone pain, tiredness, unusual sweating, nausea, diarrhea, dizziness, and trouble sleeping.
• Notify your doctor or pharmacist promptly if any of these effects persist or worsen.
• The medication is prescribed because its benefits outweigh potential side effects, and many users don’t experience severe issues.
• Report serious side effects to your doctor immediately, such as persistent nausea/vomiting, bone fractures, joint/muscle/tendon pain or swelling, mental/mood changes (like depression, anxiety), vaginal bleeding, unusual tiredness, dark urine, or yellowing of eyes/skin.
• Exemestane and cancer may rarely lead to severe blood clot-related problems (e.g., heart attack or stroke). Seek immediate medical help if you experience sudden shortness of breath, chest/jaw/left arm pain, confusion, coughing up blood, sudden dizziness/fainting, pain/swelling/warmth in the groin/calf, tingling/weakness/numbness in the arms/legs, trouble speaking, swelling of arms/legs, weakness on one side of the body, vision changes, or sudden/severe headache.
• Although a serious allergic reaction is rare, seek immediate medical help if you observe symptoms such as rash, itching/swelling (especially face/tongue/throat/neck), severe dizziness, or trouble breathing.
• The provided list is not exhaustive; contact your doctor or pharmacist if you notice other effects not mentioned.

Precautions

• Inform your doctor or pharmacist about any allergies to Exemestane or other substances, as inactive ingredients may cause allergic reactions or other issues.
• Share your medical history with your doctor or pharmacist, especially high blood fats (cholesterol), bone problems (osteopenia, osteoporosis), stroke or blood clots, heart disease (chest pain, heart attack, heart failure), high blood pressure, kidney problems, and liver problems.
• This drug may cause dizziness or fatigue. Alcohol or marijuana (cannabis) can intensify these effects. Avoid activities requiring alertness until safe to do so. Limit alcohol intake. Discuss marijuana usage with your doctor.
• Before surgery, inform your doctor or dentist about all products you use, including prescriptions, non-prescriptions, and herbal items.
• Exemestane must not be used during pregnancy due to potential harm to the unborn baby. It is primarily for use in postmenopausal women. If near menopause or not through menopause, discuss reliable birth control with your doctor, continuing its use for 1 month after stopping Exemestane. Do not use birth control with estrogen. Inform your doctor promptly if you become pregnant.
• It is unknown if Exemestane passes into breast milk. Breastfeeding is not recommended while using this drug and for 1 month after stopping. Consult your doctor before breastfeeding.