Indications
- Nonsteroidal anti-inflammatory drug (NSAID), specifically a COX-2 inhibitor.
- Relieves pain and inflammation, used for arthritis, acute pain, and menstrual pain.
- Enhances the ability to perform normal daily activities.
- If treating a chronic condition, consult the doctor about non-drug treatments and alternative medications for pain relief.
- Works by blocking the enzyme that produces prostaglandins in the body.
- Reduction in prostaglandins contributes to the alleviation of pain and swelling.
Dosage and administration
- Read the Medication Guide provided by the pharmacist before starting celecoxib, and with each refill. Direct questions to the doctor or pharmacist.
- Take orally as directed by the doctor, usually once or twice daily, preferably with food to minimize stomach upset.
- Dosage depends on medical condition and treatment response. Use the lowest effective dose for the prescribed duration.
- Take with a full glass of water unless directed otherwise by the doctor.
- Avoid lying down for at least 10 minutes after taking the medication.
- For certain conditions like arthritis, it may take up to two weeks of regular use to experience the full benefit.
- If using on an “as needed” basis, take at the first signs of pain for optimal effectiveness. Delaying may reduce its efficacy.
Side effects
- Stomach upset or gas may occur; inform the doctor or pharmacist if persistent or worsening.
- Medication prescribed due to the doctor’s judgment of benefits outweighing risks; many users don’t experience serious side effects.
- May elevate blood pressure; monitor regularly and report high readings to the doctor.
- Report immediately to the doctor any severe headache, pain/swelling/warmth in the groin/calf, signs of kidney problems, difficult/painful swallowing, or symptoms of heart failure.
- Rare but serious liver disease may occur; seek medical help for symptoms like persistent nausea/vomiting, loss of appetite, dark urine, severe stomach/abdominal pain, yellowing eyes/skin.
- Very serious allergic reactions are rare; seek immediate medical help for symptoms like fever, swollen lymph nodes, rash, itching/swelling (especially face/tongue/throat), severe dizziness, trouble breathing.
- Not an exhaustive list of possible side effects; contact the doctor or pharmacist for any unlisted effects.
Precautions
- Before taking celecoxib, inform the doctor/pharmacist of allergies to it, aspirin, other NSAIDs, or COX-2 inhibitors. Check with the pharmacist for inactive ingredients.
- Share medical history, especially asthma, liver disease, stomach/intestine/esophagus issues, heart disease, high blood pressure, stroke, blood disorders, and nasal polyps.
- Kidney problems may arise, especially if dehydrated, have heart failure, kidney disease, are an older adult, or take specific medications; stay hydrated and report changes in urine to the doctor.
- Potential for stomach bleeding; alcohol and tobacco use, especially combined with the medicine, may increase the risk; limit consumption and consult the doctor or pharmacist.
- Inform the doctor or dentist about all products used, including prescription drugs, nonprescription drugs, and herbal products, before surgery.
- Older adults may have a higher risk of stomach/intestinal bleeding, kidney problems, heart attack, and stroke.
- Caution with systemic onset juvenile rheumatoid arthritis in children due to an increased risk of serious bleeding/clotting problems.
- Women of childbearing age should discuss benefits and risks with their doctor. Inform the doctor if pregnant or planning to become pregnant. Not recommended after 30 weeks of pregnancy.
- Medication passes into breast milk; consult the doctor before breastfeeding.
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