Combination medication for high pressure inside the eye (glaucoma or ocular hypertension).
Contains brimonidine and timolol.
Treats open-angle glaucoma or eye diseases.
Lowers eye pressure to prevent blindness.
Brimonidine enhances fluid drainage and reduces fluid formation.
Timolol decreases fluid formation in the eye.
Not recommended for children under 2 years old due to increased risk of serious side effects.
Dosage and administration
Read the Patient Information Leaflet before using the product.
Wash hands before applying eye drops.
Avoid touching dropper tip or letting it touch eyes or surfaces.
Remove contact lenses before using the eye drops.
Wait 15 minutes after using the medication before putting in contact lenses.
Tilt head back, look up, pull down lower eyelid, place 1 drop in pouch, 2 times daily.
Close eyes for 1-2 minutes, apply gentle pressure at corner of the eye.
Repeat steps for the other eye if directed.
Do not rinse the dropper, replace cap after each use.
Wait at least 10 minutes before applying other eye medications.
Use regularly at the same times each day.
Continue use even if feeling well.
Side effects
Temporary blurred vision, burning, stinging, itching, redness of the eye.
Watery eyes, dry eyes, dry mouth, sensation of something in the eye.
Headache, dizziness, drowsiness.
Inform your doctor if these effects persist or worsen.
Serious side effects: vision changes, eye sensitivity to light, eye pain, slow/irregular heartbeat.
Muscle weakness, unusual tiredness, mental/mood changes, coldness/numbness/pain in hands or feet.
Swelling ankles/feet, sudden unexplained weight gain, shortness of breath.
Seek medical help for very serious side effects: persistent dizziness, trouble breathing, chest pain.
Weakness on one side of the body, trouble speaking, confusion, fainting.
Very serious allergic reaction is rare; seek immediate medical help for symptoms like rash, swelling, severe dizziness, trouble breathing.
Not a complete list of possible side effects; contact your doctor for other effects.
Precautions
Inform your doctor about allergies to brimonidine, timolol, apraclonidine, or other allergies.
Provide medical history, especially lung disease, irregular heartbeats, heart disease, kidney/liver disease, blood vessel disorders, circulation issues, orthostatic hypotension, diabetes, depression, overactive thyroid, muscle weakness disorders, severe allergies.
Consult your doctor if you have an eye infection, injury, or surgery, and inquire about using the medication.
Inform your surgeon or dentist about all products you use before surgery.
This medication may mask symptoms of low blood sugar but doesn’t affect other symptoms; monitor blood sugar regularly if you have diabetes.
May impact blood sugar control in diabetes; notify your doctor of symptoms of high blood sugar.
May cause dizziness, drowsiness, or blurred vision; avoid activities requiring alertness until safe.
Limit alcohol/marijuana use; discuss marijuana use with your doctor.
Use during pregnancy only if necessary; discuss risks and benefits with your doctor.
Unlikely to harm a nursing infant but consult your doctor before breastfeeding.
Additional information
Brand Name:
Combigan
Scientific Name:
Brimonidine Tartrate/Timolol Maleate
Other Names:
Brimocom, Combigan
Strength(s):
0.2/0.5%
Quantities Available:
5mL, 10mL, 15mL
Formulation:
Eye Drops
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Combigan
Brimonidine Tartrate/Timolol Maleate
