DILANTIN treats tonic-clonic and psychomotor seizures.
It also prevents and treats seizures during or after neurosurgery.
Dosage and administration
Adult starting dose: 100 mg DILANTIN extended capsule three times daily, with adjustments as needed.
Satisfactory maintenance dose for most adults: One capsule three to four times daily, possibly increasing to two capsules three times daily if necessary.
Once-a-day dosage for adults: Consider 300 mg DILANTIN extended capsule if seizure control is established with three daily doses.
Adult loading dose: For rapid steady-state serum levels in clinic or hospital settings, refer to full prescribing information.
Pediatric starting dose: 5 mg/kg/day in two to three equally divided doses, up to a maximum of 300 mg daily. Maintenance dosage: 4 to 8 mg/kg/day.
Serum blood level determinations may be necessary for optimal dosage adjustments, with clinically effective serum total concentration of 10 to 20 mcg/mL (unbound phenytoin concentration: 1 to 2 mcg/mL).
Side effects
Nystagmus
Ataxia
Slurred speech
Decreased coordination
Somnolence
Mental confusion.
Precautions
Withdrawal Precipitated Seizure: May cause status epilepticus; dose reductions or discontinuation should be gradual.
Suicidal Behavior and Ideation: Monitor for depression, suicidal thoughts, or unusual mood or behavior changes.
Serious Dermatologic Reactions: Discontinue at first sign of rash; if suggestive of SJS/TEN, discontinue permanently and consider alternative therapy.
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)/Multiorgan Hypersensitivity: Evaluate immediately for signs of hypersensitivity; discontinue if alternative cause cannot be established.
Cardiac Effects: Reports of bradycardia and cardiac arrest.
Angioedema: Discontinue if symptoms like facial swelling occur.
Hepatic Injury: Cases of acute hepatotoxicity reported; discontinue immediately.
Hematopoietic Complications: If occurs, follow-up observation needed; consider alternative treatment.
Additional information
Scientific Name:
Phenytoin Sodium
Formulation:
Capsule, ER Capsule, Tablet
Strength(s):
30mg, 100mg
Quantities Available:
100, 120, 200, 300
All product content included on OnlineCanadianPharmacy.com is for information only. Please note that it is not a replacement for your individual professional medical care or advice. Always remember to speak with a qualified health professional before taking any prescription or non prescription medication.
At present, a power outage is affecting some of our services including our call center, email, and live chat. Our customer service is of the utmost importance and our team will tirelessly work until these services may resume. We apologize for any delays or hardships caused by this disruption in service, -- thank you for your patience.
Dilantin
Phenytoin Sodium
