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Indications

• Methenamine is used to prevent or control recurring urinary tract infections caused by specific bacteria.
• It is not intended for treating active infections; antibiotics should be used first for infection treatment and cure.
• Methenamine inhibits bacteria growth in urine and includes an ingredient to acidify urine.
• Acidic urine causes methenamine to convert into formaldehyde, which eliminates bacteria.
• The drug is effective solely against bacterial infections in the urinary tract.
• It does not work for other bacterial infections (e.g., in the blood) or viral infections (e.g., common cold or flu).
• Misuse of antibacterial drugs, including methenamine, can reduce their effectiveness.

Dosage and administration

• Take the medication orally as directed by your doctor.
• Dosage depends on the prescribed brand of methenamine, your medical condition, and your treatment response.
• For children, dosage is determined by age and weight.
• Methenamine is more effective with acidic urine; your doctor may test and recommend ways to increase urine acidity.
• Methods to boost urine acidity may include taking vitamin C, drinking cranberry juice, and limiting certain foods/medications.
• Follow your doctor’s instructions and refer to the Drug Interactions section.
• Take the drug at regular intervals for optimal effectiveness; establish a consistent daily schedule.
• Inform your doctor if urinary tract infection symptoms reoccur (e.g., burning/painful/frequent urination).

Side effects

• Possible side effects of methenamine include nausea, vomiting, diarrhea, abdominal cramps, and loss of appetite.
• If these effects persist or worsen, notify your doctor or pharmacist promptly.
• Painful or difficult urination may occur less frequently; report such side effects to your doctor.
• Your doctor may adjust your methenamine dose or alter treatment if urinary issues arise.
• The prescribed medication is based on the doctor’s assessment of benefits outweighing potential side effects.
• Many users experience this medication without serious side effects.
• Exceeding recommended doses may lead to bladder irritation, painful/frequent urination, and bloody/pink urine; inform your doctor immediately if such symptoms occur.
• Report promptly any serious side effects, such as mouth sores, unusual headache, ringing in the ears, muscle cramps, or swelling of the arms/legs.
• Although rare, a severe allergic reaction may occur; seek medical help if symptoms like rash, itching/swelling, severe dizziness, or trouble breathing arise.
• The provided information does not cover all potential side effects; contact your doctor or pharmacist if you observe other effects not mentioned.

Precautions

• Inform your doctor or pharmacist about any allergies to methenamine, formaldehyde, or other substances before taking the medication.
• Check with your pharmacist for information on potential allergic reactions due to inactive ingredients in the product.
• Prior to using methenamine, disclose your medical history to your doctor or pharmacist, especially if you have kidney problems, liver problems, or a history of dehydration.
• Before undergoing surgery, inform your doctor or dentist about all the products you are using, including prescription drugs, nonprescription drugs, and herbal products.
• Use this medication during pregnancy only if necessary; discuss potential risks and benefits with your doctor.
• Methenamine passes into breast milk, and its impact on nursing infants is unknown; consult your doctor before breastfeeding.