Indications
- Linaclotide is used to treat specific bowel issues, including irritable bowel syndrome with constipation, chronic idiopathic constipation, and functional constipation.
- It operates by increasing fluid in the intestines and promoting the swift movement of food through the gut.
- Linaclotide aims to enhance stool texture and alleviate symptoms like bloating, abdominal pain/discomfort, straining, and sensations of incomplete bowel movements.
Dosage and administration
- Read the Medication Guide provided by your pharmacist before starting linaclotide and with each refill. Consult your doctor or pharmacist for any questions.
- Take the medication orally as directed by your doctor, usually once daily on an empty stomach, at least 30 minutes before a meal. Swallow the capsules whole without breaking or chewing them.
- If swallowing the capsule is difficult, it can be opened, and the contents mixed with a teaspoonful of applesauce. Consume the mixture immediately without saving it for later use.
- Alternatively, empty the capsule into an ounce (30 milliliters) of water, swirl for 20 seconds, and drink immediately. Add another ounce (30 milliliters) of water, swirl for 20 seconds, and drink to ensure the entire dose is taken. The water mixture can also be administered through a tube into the stomach (nasogastric or gastric tube) with instructions from a healthcare professional.
- The dosage is determined by your medical condition and response to treatment.
- Take the medication regularly at the same time each day for maximum benefits.
- Inform your doctor if your condition does not improve or worsens.
Side effects
- Diarrhea, bloating, gas, or stomach/abdominal pain/discomfort may occur. Notify your doctor or pharmacist if these effects persist or worsen.
- This medication is prescribed because the perceived benefit outweighs the risk of side effects, and many users do not experience serious side effects.
- Stop taking the medication and inform your doctor immediately if you encounter severe diarrhea.
- While a severe allergic reaction is rare, seek immediate medical help if you observe symptoms such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or difficulty breathing.
- This list does not cover all possible side effects; contact your doctor or pharmacist if you notice other effects not mentioned here.
Precautions
- Inform your doctor or pharmacist about any allergies to linaclotide or other substances in the product, as it may contain inactive ingredients that can cause allergic reactions.
- Share your medical history with your doctor, particularly if you have a history of stomach or intestinal blockage.
- Before undergoing surgery, disclose all the products you use, including prescription and nonprescription drugs, as well as herbal products, to your doctor or dentist.
- Use this medication during pregnancy only if essential and discuss the potential risks and benefits with your doctor.
- Consult your doctor before breastfeeding, as it is unclear whether this medication passes into breast milk.
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