Indications
- Prucalopride is used to treat chronic constipation when other medications haven’t helped.
- It works by improving how your gut moves food through your system.
Dosage and administration
- Before taking prucalopride, read the information leaflet from your pharmacist and ask your doctor or pharmacist if you have any questions.
- Take prucalopride by mouth, with or without food, as directed by your doctor, usually once a day. The usual dose is 2 milligrams.
- Take it regularly at the same time each day to get the most benefit. Tell your doctor if you don’t feel relief after 3 to 4 days.
- Your doctor may recommend additional medication for short-term constipation relief. Follow your doctor’s instructions carefully and ask how long to take prucalopride and/or other constipation medications.
Side effects
- Prucalopride may cause nausea, stomach pain, diarrhea, headache, dizziness, or tiredness in the first few days. These are usually mild and go away on their own.
- Tell your doctor if any side effects are bothersome or do not go away.
- Get medical help right away if you experience:
- Severe or ongoing stomach pain
- Bloody diarrhea or rectal bleeding
- Fast or irregular heartbeat
- Depression, thoughts of suicide, or other mental mood changes
- Allergic reaction symptoms like rash, itching, swelling, dizziness, or trouble breathing.
Precautions
- Talk to your doctor before taking prucalopride if you have allergies, diabetes, heart problems, kidney problems, liver disease, mental health issues, or stomach/intestinal issues.
- Prucalopride may cause dizziness. Avoid alcohol, marijuana, driving, or machinery until you know how it affects you.
- Tell your doctor about all medications you take, including prescriptions, over-the-counter drugs, and herbs, before surgery or dental work.
- Pregnant or breastfeeding women should discuss risks and benefits with their doctor before taking prucalopride.