Nicotinic Acid
Overview
- Niacin, a B vitamin, is produced by the body and aids in converting food into energy.
- It plays a role in maintaining a healthy nervous system, digestive system, and skin.
- Niacin is commonly found in daily multivitamins, and sufficient amounts are typically obtained through food sources like yeast, milk, meat, tortillas, and cereal grains.
- Prescription niacin (Niacor, Niaspan) is used to help manage cholesterol levels.
- The recommended daily intake is 16 mg for adult males and 14 mg for non-pregnant adult women.
Dosage and administration
- Orally taken niacin in appropriate amounts is generally considered safe.
- Serious side effects are more likely with daily doses ranging from 2,000 to 6,000 mg of niacin.
- In case of a suspected niacin overdose, immediate medical attention is advised.
Side effects
- Intense skin flushing accompanied by dizziness.
- Rapid heartbeat
- Itching
- Nausea and vomiting
- Abdominal pain
- Diarrhea
- Gout
- Liver damage
- Diabetes
Precautions
- Avoid large amounts of niacin if you have liver disease, peptic ulcer disease, or severe low blood pressure (hypotension).
- Niacin has been associated with liver damage, hypotension, and potential activation of a peptic ulcer.
- Use niacin cautiously if you have allergies, gallbladder disease, or certain thyroid disorders, as it may worsen symptoms.
- Diabetic individuals should exercise caution when using niacin, as it can interfere with blood glucose control.
- People with gout, a form of arthritis, should be cautious with niacin, as it can lead to elevated uric acid levels and increase the risk of gout.
- Pregnant individuals should avoid prescription niacin for high cholesterol, but using niacin in recommended amounts to prevent or treat niacin deficiency during pregnancy and breastfeeding is likely safe.
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