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Indications

• Revatio is indicated for the treatment of pulmonary arterial hypertension (PAH) in adults to improve exercise capacity and delay clinical worsening.
• It is prescribed to help reduce pulmonary vascular resistance and improve hemodynamic parameters in patients with PAH.
• Revatio may also be used off-label to treat other conditions such as erectile dysfunction, particularly in cases where sildenafil, the active ingredient in Revatio, is prescribed for this purpose.

Dosage and administration

• The recommended dosage of Revatio for the treatment of pulmonary arterial hypertension (PAH) in adults is 20 mg orally three times daily.
• Revatio should be taken approximately 4 to 6 hours apart.
• The dosage may be adjusted based on individual response and tolerability, up to a maximum dosage of 20 mg orally three times daily.
• Revatio can be taken with or without food.
• If a dose of Revatio is missed, it should be taken as soon as remembered, unless it is almost time for the next scheduled dose. In that case, the missed dose should be skipped, and the next dose should be taken at the regular time.
• Do not exceed the recommended dosage or frequency of administration without consulting your healthcare provider.
• For the treatment of erectile dysfunction, the recommended dosage of Revatio is 50 mg as needed approximately 1 hour before sexual activity. The dosage may be adjusted based on individual response and tolerability, up to a maximum dosage of 100 mg once daily.
• Revatio should not be used in combination with other medications containing sildenafil or other phosphodiesterase inhibitors.
• Store Revatio tablets at room temperature away from moisture and heat.

Side effects

• Common side effects of Revatio may include headache, flushing, or dizziness.
• Some individuals may experience nasal congestion, indigestion, or diarrhea while taking Revatio.
• Revatio may cause visual disturbances, such as changes in color vision or blurred vision.
• Other potential side effects include nausea, vomiting, or muscle pain.
• In rare cases, Revatio may lead to more serious side effects such as priapism (prolonged erection), sudden hearing loss, or fainting.
• Revatio may interact with certain medications, particularly nitrates or alpha-blockers, leading to a sudden drop in blood pressure.
• If you experience any severe or persistent side effects while taking Revatio, seek medical attention promptly.
• It’s important to discuss any concerns or side effects with your healthcare provider.

Precautions

• Inform your healthcare provider about any history of heart problems, including heart attack, irregular heartbeat, or heart failure, before starting Revatio.
• Use caution when taking Revatio if you have a history of hypotension (low blood pressure) or hypertension (high blood pressure).
• Discuss with your healthcare provider if you have any liver or kidney problems, as dosage adjustments may be necessary when taking Revatio.
• Avoid consuming grapefruit or grapefruit juice while taking Revatio, as it may increase the levels of sildenafil in your blood, leading to an increased risk of side effects.
• Inform your healthcare provider about all medications you are currently taking, including prescription, over-the-counter, and herbal supplements, as they may interact with Revatio.
• If you experience sudden vision loss or hearing loss while taking Revatio, seek immediate medical attention.
• Do not abruptly stop taking Revatio without consulting your healthcare provider, as it may lead to worsening of your condition.
• If you experience chest pain, dizziness, or nausea during sexual activity after taking Revatio, seek immediate medical attention.