Indications
- Semaglutide is used in conjunction with a proper diet and exercise regimen to manage high blood sugar in individuals with type 2 diabetes.
- Its role is crucial in preventing complications associated with diabetes, including kidney damage, blindness, nerve problems, limb loss, and sexual function issues.
- Effective diabetes control with semaglutide may also reduce the risk of heart attacks and strokes.
- Semaglutide mimics a natural hormone (incretin) in the body.
- The medication functions by triggering the release of insulin in response to elevated blood sugar levels, such as those occurring after a meal.
- Additionally, semaglutide works to decrease the production of sugar by the liver.
Dosage and administration
- Read the Medication Guide from your pharmacist before starting semaglutide and with each refill. Ask your doctor or pharmacist if you have any questions.
- Take the medication with a sip of plain water, usually once daily, as directed by your doctor. Do not use any other beverage. Swallow the tablet whole; do not split, chew, or crush it.
- Wait at least 30 minutes after taking semaglutide before eating or drinking anything other than plain water and before taking other oral medications.
- For optimal effectiveness, eat 30 to 60 minutes after taking semaglutide. Maintain consistency in how you take this medication with each dose.
- Dosage is determined by your medical condition and response to treatment.
- To minimize side effects, your doctor may advise starting at a low dose and gradually increasing it. Follow instructions carefully.
- Take the medication regularly at the same time daily to maximize benefits.
- Do not exceed the prescribed dose or use the drug more frequently or for a longer duration than instructed. This won’t hasten improvement and increases the risk of side effects.
- Inform your doctor if your condition does not improve or worsens (e.g., if your blood sugar remains too high or too low).
Side effects
- Common side effects of semaglutide may include nausea, vomiting, abdominal pain, loss of appetite, diarrhea, or constipation. Nausea often improves with continued use. If these effects persist or worsen, inform your doctor or pharmacist.
- The medication is prescribed because your doctor believes the benefits outweigh the risks. Many people using semaglutide do not experience serious side effects.
- Notify your doctor promptly if you experience serious side effects such as signs of kidney problems (e.g., changes in urine amount) or vision changes (e.g., decreased/blurred vision).
- Seek immediate medical help for very serious side effects, including signs of pancreas or gallbladder disease (persistent nausea/vomiting, severe abdominal pain).
- While semaglutide alone typically does not cause low blood sugar (hypoglycemia), it may occur when combined with other diabetes medications. Discuss with your doctor or pharmacist whether adjustments to other diabetes medication doses are necessary. Factors like excessive alcohol consumption, insufficient calorie intake, or intense exercise can also lead to low blood sugar. Carry glucose tablets or gel to address low blood sugar symptoms and consult your healthcare provider if you miss a meal.
- Symptoms of high blood sugar (hyperglycemia) include increased thirst/urination. Report these symptoms promptly to your doctor, who may need to adjust your diabetes treatment plan.
- A severe allergic reaction to semaglutide is rare but requires immediate medical attention. Seek help if you notice symptoms like rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or difficulty breathing.
- This list does not cover all potential side effects. Contact your doctor or pharmacist if you observe any other effects not mentioned above.
Precautions
- Inform your doctor or pharmacist about any allergies to semaglutide or other substances. Inactive ingredients in the product may cause allergic reactions or other issues.
- Before using semaglutide, disclose your medical history, especially if you have diabetic retinopathy, pancreatitis, gallbladder disease, kidney problems, or stomach/intestinal disorders.
- Due to potential effects on blood sugar levels, be cautious about activities requiring alertness or clear vision, as semaglutide may cause blurred vision, dizziness, or drowsiness.
- Limit alcohol consumption while using this medication, as it may increase the risk of low blood sugar.
- Managing blood sugar may be challenging during stressful periods (fever, infection, injury, surgery). Consult your doctor for potential adjustments to your treatment plan, medications, or blood sugar testing.
- Inform your doctor or dentist about all products you use, including prescriptions, over-the-counter drugs, and herbal products, before undergoing surgery.
- If considering pregnancy, consult your doctor about the benefits and risks of using semaglutide. The manufacturer recommends discontinuing the medication two months before planned pregnancy.
- Pregnancy can affect or worsen diabetes; discuss a blood sugar management plan with your doctor. Diabetes treatment, including diet and medications such as insulin, may be adjusted during pregnancy.
- It is unclear if semaglutide passes into breast milk. Consult your doctor before breastfeeding.
- For additional information, consult your pharmacist or physician.
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