Indications
- Synjardy is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
- It is prescribed for patients who are already taking empagliflozin and metformin separately or who are already taking both empagliflozin and metformin as separate components.
- Synjardy combines empagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, and metformin, a biguanide, to help lower blood sugar levels in patients with type 2 diabetes.
Dosage and administration
- The dosage of Synjardy should be individualized based on the patient’s current regimen of empagliflozin and metformin, as well as their glycemic control.
- Synjardy is typically taken orally in tablet form, with or without food, as prescribed by a healthcare provider.
- The recommended starting dose of Synjardy is usually based on the patient’s current regimen of empagliflozin and metformin.
- The dosage strengths of empagliflozin and metformin in Synjardy are available in various combinations to allow for dose titration and optimization of glycemic control.
- The tablets should be swallowed whole with a full glass of water. They should not be crushed, chewed, or split.
- Patients should continue to monitor their blood sugar levels regularly as directed by their healthcare provider while taking Synjardy.
- If a dose of Synjardy is missed, it should be taken as soon as remembered, unless it is almost time for the next dose. In that case, the missed dose should be skipped, and the regular dosing schedule resumed.
- Patients should not double the dose to make up for a missed one.
- If there are any questions or concerns about the dosage or administration of Synjardy, patients should consult their healthcare provider or pharmacist for guidance.
Side effects
- Common side effects of Synjardy may include urinary tract infections, genital yeast infections, or increased urination.
- Some individuals may experience dehydration, dizziness, or low blood pressure while taking Synjardy.
- Synjardy can cause symptoms of hypoglycemia (low blood sugar), such as shakiness, sweating, or confusion, especially when used in combination with other diabetes medications.
- It may also lead to gastrointestinal side effects such as nausea, vomiting, or diarrhea.
- Synjardy may increase the risk of bone fractures or ketoacidosis (a serious complication of diabetes) in some patients.
- Rarely, allergic reactions such as rash, itching, or swelling of the face, lips, or throat may occur with the use of Synjardy.
- Contact your healthcare provider if you experience any persistent or severe side effects while taking Synjardy.
Precautions
- Inform your healthcare provider about any existing medical conditions, especially kidney problems, heart disease, or history of urinary tract infections, before taking Synjardy.
- Let your healthcare provider know if you are pregnant, planning to become pregnant, or breastfeeding, as Synjardy may not be suitable during pregnancy or lactation.
- Inform your healthcare provider if you have a history of allergies to medications or any other substances, as Synjardy may contain inactive ingredients that can cause allergic reactions.
- Use caution when taking Synjardy if you are elderly or have impaired kidney function, as it may increase the risk of dehydration or low blood pressure.
- Monitor your blood sugar levels regularly while taking Synjardy, and be aware of the signs and symptoms of hypoglycemia or hyperglycemia.
- Stay adequately hydrated while taking Synjardy, especially during hot weather or when engaging in vigorous physical activity.
- Avoid excessive alcohol consumption while taking Synjardy, as it may increase the risk of hypoglycemia or other side effects.
- Inform your healthcare provider about all medications, supplements, and herbal remedies you are taking, as they may interact with Synjardy and affect its effectiveness or increase the risk of side effects.
- Take Synjardy exactly as prescribed by your healthcare provider, and do not adjust the dosage or frequency of administration without consulting them.
- Store Synjardy at room temperature away from moisture and heat and keep it out of reach of children and pets.