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Indications

• Tradjenta is indicated for the treatment of type 2 diabetes mellitus in adults.
• It is prescribed to improve glycemic control by lowering blood sugar levels in patients with type 2 diabetes.
• Tradjenta may be used alone or in combination with other antidiabetic medications, such as metformin, sulfonylureas, or insulin, to achieve target glucose levels.

Dosage and administration

• The recommended dosage of Tradjenta is 5 mg taken orally once daily.
• Tradjenta can be taken with or without food at any time of the day.
• For patients with renal impairment (creatinine clearance less than 45 mL/min), the dosage of Tradjenta should be adjusted to 2.5 mg once daily.
• No dosage adjustment is necessary for patients with mild to moderate hepatic impairment.
• Tradjenta should be swallowed whole with a glass of water and should not be crushed, chewed, or broken.
• If a dose of Tradjenta is missed, it should be taken as soon as remembered, unless it is almost time for the next dose. In that case, the missed dose should be skipped, and the regular dosing schedule resumed.
• Patients should not take more than the prescribed dose of Tradjenta without consulting their healthcare provider.
• If there are any questions or concerns about the dosage or administration of Tradjenta, patients should consult their healthcare provider or pharmacist for guidance.

Side effects

• Common side effects of Tradjenta may include upper respiratory tract infection, nasopharyngitis, or headache.
• Some individuals may experience urinary tract infection, nasopharyngitis, or sore throat while taking Tradjenta.
• Tradjenta may also lead to hypersensitivity reactions, such as rash, itching, or swelling of the face, lips, or throat, in rare cases.
• It may increase the risk of pancreatitis, characterized by severe abdominal pain, nausea, or vomiting, particularly in patients with a history of pancreatitis.
• Tradjenta may cause hypoglycemia (low blood sugar) when used in combination with insulin or sulfonylureas, resulting in symptoms such as sweating, trembling, or confusion.
• Rarely, Tradjenta may lead to kidney problems or urinary tract infections, particularly in patients with pre-existing renal impairment.
• Contact your healthcare provider if you experience any persistent or severe side effects while taking Tradjenta.

Precautions

• Inform your healthcare provider about any existing medical conditions, especially kidney problems, pancreatitis, or hypersensitivity reactions, before taking Tradjenta.
• Let your healthcare provider know if you are pregnant, planning to become pregnant, or breastfeeding, as the safety of Tradjenta during pregnancy or lactation has not been established.
• Inform your healthcare provider if you have a history of allergies to medications or any other substances, as Tradjenta may contain inactive ingredients that can cause allergic reactions.
• Use caution when taking Tradjenta if you have a history of hypoglycemia (low blood sugar) or if you are taking other antidiabetic medications, as it may increase the risk of hypoglycemia.
• Monitor for signs and symptoms of pancreatitis, such as severe abdominal pain, nausea, or vomiting, while taking Tradjenta.
• Inform your healthcare provider about all medications, supplements, and herbal remedies you are taking, as they may interact with Tradjenta and affect its effectiveness or increase the risk of side effects.
• Keep Tradjenta out of reach of children and pets, and store it at room temperature away from moisture and heat.
• Follow up with your healthcare provider regularly to monitor your response to Tradjenta and adjust the treatment plan as needed.